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Arf1 kontrollerar proliferation av bröstcancerceller genom att reglera

AGAP2: Gene description i. ArfGAP with GTPase domain, ankyrin repeat and PH domain 2: Predicted location i Intracellular: Number of transcripts i. 4: HUMAN PROTEIN ATLAS INFORMATION i. Summary i. Mainly localized to the nucleoplasm Genes; AGAP2; AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) active file. The Function of AGAP2. GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity.

To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assays. The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells and promotes cancer cell invasion. Entrez_Gene (NCBI) AGAP2 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Aliases: CENTG1; GGAP2; PIKE: GeneCards (Weizmann) AGAP2: Ensembl hg19 (Hinxton) ENSG00000135439 [Gene_View] Ensembl hg38 (Hinxton) ENSG00000135439 [Gene_View] ENSG00000135439 [Sequence] chr12:57723761-57742161 [Contig_View] AGAP2 [Vega] ICGC DataPortal agap2 ID ZDB-GENE-061103-343 Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Symbol agap2 Nomenclature History Previous Names.

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Agap2 gene expression in Bgee. Bgee allows to automatically compare gene expression patterns between species, by referencing expression data on anatomical ontologies, and designing homology relationships between them. Symbol, synonyms, gene family about AGAP2 and general information of AGAP2 protein, AGAP2 gene, et al.

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ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. Synonyms. Centg1, PIKE-A, PIKE-L Feature Type Gene expression databases. Bgee i: ENSG00000135439, Expressed in right AGAP2. 169: Annotation score: Sequence caution i 100130776 - Gene ResultAGAP2-AS1 AGAP2 antisense RNA 1 [ (human)] AGAP2-AS1 AGAP2 antisense RNA 1 [ (human)] AGAP2-AS1 is a prognostic biomarker for patients with GBM, and functions as an oncogenic lncRNA to modulate GBM cell proliferation, apoptosis, migration, and invasion, which suggests that AGAP2-AS1 is potential therapeutic target for GBM. Panel Description Sequence variants and/or copy number variants (deletions/duplications) within the AGAP2 gene will be detected with >99% sensitivity. Variants classified as unknown significance (VUS), likely pathogenic, or pathogenic will be reported. Benign and likely benign variants are generally not reported.

Tested in ELISA, IHC, WB Gene/Protein Basic Information For AGAP2 (Source: Uniprot.org, NCBI) Proteintech Anti-AGAP2 Polyclonal, Catalog # 14690-1-AP. Tested in Western The protein encoded by this gene belongs to the centaurin gamma-like family.
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Gene name: AGAP2 (HGNC Symbol) Synonyms: CENTG1: Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (HGNC Symbol) Chromosome: 12: Cytoband: q14.1: Chromosome location (bp) 57723761 - 57742157: Number of transcripts i 100130776 - Gene ResultAGAP2-AS1 AGAP2 antisense RNA 1 [ (human)] AGAP2-AS1 AGAP2 antisense RNA 1 [ (human)] AGAP2-AS1 is a prognostic biomarker for patients with GBM, and functions as an oncogenic lncRNA to modulate GBM cell proliferation, apoptosis, migration, and invasion, which suggests that AGAP2-AS1 is potential therapeutic target for GBM. The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells and promotes cancer cell invasion. Gene information about ENSG00000135439 / AGAP2 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 agap2 – vi är en europeisk konsult- och ingenjörskoncern som erbjuder specialistkunskap inom flera industrier. Koncernen stöttar kunder genom att hjälpa dem att genomföra projekt för att leda företagen mot tillväxt. Vi erbjuder expertis och hög kompetens inom alla områden vi är verksamma.

Every primer pair is optimized, experimentally validated, and performance guaranteed. ASAP2 (ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 2) is a Protein Coding gene. Diseases associated with ASAP2 include Bulbar Polio and Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly. Among its related pathways are Endocytosis and Fc gamma R-mediated phagocytosis. 2019-01-01 · Gene functional annotation revealed that Agap2 mainly participated in the metabolic and developmental process in gene body region and the metabolic process in the promoter region. KEGG pathway analysis showed that DMR located in Agap2 gene promoter area was enriched in the signal transduction, especially in the FOXO signal pathway, which may be associated with insulin signal transduction.
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SEEK provides biologists with a way to navigate the massive human expression compendium that Pediatric Pan-Cancer (DKFZ, Nature 2017). 961 samples. Pediatric Pan-cancer ( Columbia U, Genome Med 2016). 103 samples.

Entrez_Gene (NCBI) AGAP2 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Aliases: CENTG1; GGAP2; PIKE: GeneCards (Weizmann) AGAP2: Ensembl hg19 (Hinxton) ENSG00000135439 [Gene_View] Ensembl hg38 (Hinxton) ENSG00000135439 [Gene_View] ENSG00000135439 [Sequence] chr12:57723761-57742161 [Contig_View] AGAP2 [Vega] ICGC DataPortal agap2 ID ZDB-GENE-061103-343 Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Symbol agap2 Nomenclature History Previous Names. lnc.punisher (); zgc:153779; Type Gene Summary: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase.
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Agap2 - Sticky Bytes

It is overexpressed in cancer cells, and promotes cancer cell invasion. Functional Associations. AGAP2-AS1 has 521 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets. Protein attributes for AGAP2 Gene Isoform 1 interacts with EPB41L1, PLCG1, NF2, HOMER1 and HOMER2 (By similarity). Isoform 2 interacts with activated AKT1 Sequence=BAA11484.2; Type=Erroneous initiation; Evidence= {ECO:0000305}; The gene view histogram is a graphical view of mutations across AGAP2. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.

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lnc.punisher (); zgc:153779; Type Top Gene-Substance Interactions Substances That Increase AGAP2 Category: All Potential Recommendations Possibly Consumable Substances Beneficial Substances Important Natural Compounds Substances of Biological Interest Obscure Chemicals Toxins Drugs GRAS Topical Natural Treatment UCSC Genes AGAP2-AS1 (uc001sps.4) at chr12:58120023-58122139 - Homo sapiens AGAP2 antisense RNA 1 (AGAP2-AS1), non-coding RNA. AGAP2 (uc001spq.3) at chr12:58118076-58132029 - Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 1, mRNA.